Awesome List Updates on Apr 16, 2026

10 awesome lists updated today.

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1. Awesome Osint

Email Search / Email Check / GitHub

• Email Extractor - A browser-based utility to quickly extract email addresses from bulk text or raw data for further investigation.

Threat Intelligence / GitHub

• DFIR Platform - Threat intelligence platform with multi-source IOC enrichment, phishing email analysis, exposure scanning, and domain reputation scoring. Free tier available.

2. Awesome Embedded Rust

Firmware projects / WIP

• 🤖 hypervisor (⭐4): Bare-metal ARM64 Type-1 hypervisor in no_std Rust (single dependency: fdt). Runs at EL2, boots Linux with 4 vCPUs, virtio-blk/net, FF-A v1.1 SPMC at S-EL2. Targets QEMU virt machine (no real hardware tested yet).

3. Awesome Zig

Data & Science / Database

• lispking/kvdb (⭐8) - A lightweight, high-performance embedded key-value database written in Zig.

4. Awesome Ada

Sound / GPL (no linking exception)

• portable-openal-sound (⭐1) - A linux-sound-playing package for Ada apps that can asynchronously start and stop music loops, as well as initiate transient sounds.

5. Awesome Cpp

CLI

• Crossline (⭐150) - A small, self-contained, zero-config, MIT licensed, cross-platform, readline and libedit replacement. [MIT]

6. Awesome Raspberry Pi

Tools

• Armbian Imager - An open-source imaging tool that makes installing Armbian OS effortless.

• OSMC Installer - GUI based utility to download and install OSMC on to a variety of platforms.

• Raspberry Pi SD Card Lifespan Calculator - Interactive tool to estimate when your SD card will fail based on P/E cycles and Write Amplification Factor (WAF).

Projects

• PiSpot-Show (⭐1) - WiFi voucher display system with weather integration and PiJuice battery management.

• PiSpot Watch (⭐1) - Wrist-wearable Pi Zero smartwatch with e-ink display that generates Wi-Fi voucher codes on demand via button press.

• Ultimate DNS Shield (⭐0) - Self-hosted recursive DNS server using Pi-hole, Unbound and Docker on Raspberry Pi 4.

Useful Apps / Android

• EtchDroid - Is an open-source application that writes disk images to USB drives. Android

Tutorials / iOS

• Raspberry Pi 5 SSD Boot Guide - Comprehensive guide on upgrading RPi 5 with NVMe SSDs, including benchmarks and hardware compatibility tests (2026 update).

7. Awesome Mac

Utilities / General Tools

• WaifuX - Open-source ACG app for wallpapers, animated backgrounds, and anime videos.

8. Awesome Computational Biology

Preprocessing Tools

• Numbat (⭐211) — Haplotype-aware copy number variation inference from single-cell RNA-seq using hidden Markov models.

• CaSpER (⭐87) — CNV identification and visualization by integrative analysis of single-cell or bulk RNA-seq data.

• CellCharter (⭐168) — Identification and characterization of spatial cell niches from spatial transcriptomics using VAEs and Gaussian mixture models.

• STAGATE (⭐51) — Adaptive graph attention auto-encoder for spatial domain identification in spatial transcriptomics.

• NCEM (⭐117) — GNN-based model for learning intercellular communication from spatial graphs of cells.

• DeepTalk (⭐29) — Graph attention network for deciphering cell-cell communication from spatial transcriptomics data.

• COMMOT (⭐136) — Optimal transport-based framework for screening cell-cell communication in spatial transcriptomics.

• TIGON (⭐57) — Neural optimal transport method for reconstructing growth and dynamic trajectories from single-cell transcriptomics.

• LINGER (⭐127) — Neural network for gene regulatory network inference from single-cell multiome (RNA+ATAC-seq) data with bulk data pretraining.

• sciPENN (⭐18) — RNN-based method for simultaneous protein expression prediction, uncertainty estimation, and cell-type label transfer from CITE-seq and scRNA-seq data.

• MOGONET (⭐179) — Multi-omics graph convolutional network framework for patient classification and biomarker identification.

Drug Response Prediction

• PRNet (⭐78) — Deep generative model for predicting transcriptional responses to novel chemical perturbations for drug discovery.

• DRUML (⭐11) — Ensemble machine learning framework combining standard ML with deep learning to systematically rank anti-cancer drugs from proteomics and RNA-seq data.

Drug Repurposing

• TranSiGen (⭐34) — Dual-VAE architecture for ligand-based virtual screening, drug response prediction, and drug repurposing using chemical-induced transcriptional profiles.

Molecular Generation

• DiffSBDD (⭐500) — Equivariant diffusion model for structure-based drug design that generates molecules and binding conformations for protein targets.

• ReLeaSE (⭐367) — Deep reinforcement learning framework for de novo drug design combining a generative and predictive model.

• PaccMannRL (⭐10) — Reinforcement learning-based generative model for de novo hit-like anticancer molecule design from transcriptomic data.

Single-cell Foundation Models / Transcriptomics Foundation Models

• SATURN (⭐164) — Transformer-based model integrating gene expression and protein sequences via a protein language model to learn unified multi-species cell embeddings.

• CancerFoundation (⭐29) — Single-cell RNA-seq foundation model trained exclusively on a curated dataset of malignant cells to learn cancer-specific embeddings.

Single-cell Foundation Models / Spatial Foundation Models

• Nicheformer (⭐159) — Foundation model for single-cell and spatial omics using a transformer architecture with positional embeddings to encode spatial cell information.

• scGPT-spatial (⭐133) — Extension of scGPT for spatial transcriptomics with continual pretraining and a mixture-of-experts decoder for spatial gene expression analysis.

Single-cell Foundation Models / Multi-Omics Foundation Models

• Concerto (⭐40) — Contrastive self-supervised learning framework for single-cell multimodal data integration, batch correction, and reference-query mapping.

• scButterfly (⭐28) — Dual-aligned variational autoencoder for single-cell cross-modality translation between paired and unpaired multiomics data.

• JAMIE (⭐16) — Joint variational autoencoder for multimodal single-cell data imputation and embedding.

• scPair (⭐10) — Bidirectional feedforward network for single-cell multimodal analysis with cross-modality prediction leveraging single-cell atlases.

Multi-Modal Foundation Models / Protein Structure Prediction and Design

• PORPOISE (⭐241) — Pan-cancer integrative histology-genomic analysis framework using multimodal deep learning for patient stratification.

• PathomicFusion (⭐330) — Integrated framework fusing histopathology and genomic features via CNN, GNN, and attention gating for cancer diagnosis and prognosis.

• Virchow — Million-slide digital pathology foundation model using a vision transformer and self-supervised distillation for tile-level pathology image representation.

• TOAD (⭐182) — Tumor Origin Assessment via Deep-learning; weakly-supervised multi-task model predicting cancer primary origin from H&E whole-slide images.

• PLIP (⭐375) — Vision-language foundation model for pathology trained with contrastive learning on pathology image–text pairs for image classification and text-to-image retrieval.

• MUSK (⭐226) — Vision-language foundation model for precision oncology analyzing multimodal paired text and pathology image data for biomarker prediction and retrieval.

9. Awesome Db Tools

SQL / Code Generators

• sqlc - SQL-first code generator producing type-safe bindings for various languages and various databases.

• SQLDelight - SQL-first code generator producing type-safe bindings for Kotlin and various databases.

• pGenie - SQL-first code generator producing type-safe bindings for various languages and specializing on the PostgreSQL database.

10. Awesome Mongodb

Tools / Desktop

• Monghoul - MongoDB GUI with smart autocomplete, visual aggregation builder, and built-in MCP server

• Next: Apr 15, 2026